Very Shocking : Long Term Use Of Omeprazole and Esomeprazole Can increase 25% death rate

Long Term Use Of Omeprazole and Esomeprazole Can increase 25% death rate

Important Study On Omeprazole and Esomeprazole. OMEPRAZOLE Side Effects

Omeprazole and Esomeprazole जैसे कई प्रकार के PPI( Protone Pump Inhibitor) जो मुख्य रूप से गैस, छाती में जलन, अपच जैसी समस्याओ में धड्ले से बिना डॉक्टर की पर्ची के इस्तेमाल की जा रही हैं, हाल ही में हुए शोध में पता लगा है के इन दवाओं को लम्बे समय से इस्तेमाल करना काफी हानिकारक होता है. यहाँ तक कि मृत्यु के चांसेस काफी अधिक बढ़ जाते हैं. OMEPRAZOLE Side Effects

लेखक Ziyad Al-Aly, MD, director of clinical epidemiology at the VA St. Louis Healthcare System. और उनकी टीम के सदस्यों ने लगभग 5 साल तक उन लोगों का सर्वे किया जिन्होंने पेट की एसिडिटी को कम करने के लिए  Nexium (Esomeprazole) या  Prilosec (omeprazole) और H2 हिस्टामिन ब्लॉकर Ranitidine इत्यादि का उपयोग किया. OMEPRAZOLE Side Effects

जिन लोगों ने Nexium (Esomeprazole) या  Prilosec (omeprazole) का सेवन किया उनमे H2 हिस्टामिन ब्लॉकर इस्तेमाल करने वालों की तुलना में मृत्यु के चांसेस 25 % ज्यादा पाए गए. OMEPRAZOLE Side Effects

क्योकि करोड़ो लोग इन PPI का इस्तेमाल लगातार करते है तो 25 % डेथ रेट कई हजारों मौतों के लिये जिम्मेदार हो सकती है .वैसे तो इन PPI का उपयोग पेट में अलसर होने पर 2  से 8 हफ़्तों तक दिया जाता है या फिर डॉक्टर रोगी के आधार पर देता है परन्तु लोग इसको बिना डॉक्टर के दिए ही सालो तक इस्तेमाल करते रहते है जो काफी हानिकारक होता जाता है. OMEPRAZOLE Side Effects

 

Heart Burn Drugs Like Omeprazole and Esomeprazole Can Cause Death, OMEPRAZOLE Side Effects

Popular Heart burn drugs known as proton pump inhibitors may raise the chance of death, new research shows.

It’s not the first time the drugs also known as PPIs, have been linked to health dangers. Previous studies have tied the drugs to kidney  problems, dementia, and bone fracture, altough not all research has agreed.

In the new study, the odds of dying rose the longer people used the drugs, says senior study author Ziyad Al-Aly, MD, director of clinical epidemiology at the VA St. Louis Healthcare System.

For more than 5 years, his team tracked people who took prescription PPIs such as Nexium and Prilosec. He compared them with people who took other drugs that lower stomach acid known as H2 blockers. The study did not look at the use of PPI drugs that you can buy over the counter.

Compared with the H2 blocker users, “people who take PPIs for about a year have about a 25% higher risk of death,” says Al-Aly, who’s also an assistant professor of medicine at Washington University School of Medicine in St. Louis.

Because millions of people take PPIs regularly, that 25% chance could translate into thousands of deaths a year, Al-Aly said.

Still, the study is only an association — it doesn’t prove cause and effect. An industry representative says the drugs are safe when people follow the instructions on the label.

People who take the drugs should not immediately stop doing so, Al-Aly says. “I would say it is a small but significant risk,” he says. “It should prompt people to look at whether they should be on PPIs in the first place or not.”

PPIs are one of the most widely used types of drugs in the United States, with 15 million monthly prescriptions in 2015 for Nexium alone, according to research firm IMS.

Although the recommended treatment regimen for most PPIs is short — 2 to 8 weeks for ulcer, for example — many people end up taking the drugs for months or years. For some patients, doctors could determine the longer use is justified, and the study found the odds of death rose greatly when prescription-strength PPIs were taken for more than a year.

Prescription versions of both PPIs and H2 blockers treat serious conditions such as upper gastrointestinal tract bleeding, gastroesophageal reflux disease , and ulcers. Lower-dose over-the-counter versions are usually used to treat HeartBurn and indigestion.

The study received no industry funding. It is published online in BMJ Open.

 

source

https://www.webmd.com/heartburn-gerd/news/20170703/popular-heartburn-drugs-death-risk#1